An exciting opportunity has arisen for a high throughput sequencing bioinformatician within the CRUK Oxford Centre’s Clinical Next Generation Sequencing (NGS) Core Facility.
The focus of the Clinical NGS Core Facility is to provide, develop, validate and apply novel genomics technologies for clinical trials and translational research. The core is a fully clinically accredited laboratory.
The interdisciplinary nature of the service provides a diverse and stimulating array of challenges relating to biology, sequence analysis, statistics and computer programming and this, combined with projects developed from across the University cancer research community, provides an active and rich research environment.
You will be responsible for the analysis of next generation sequencing data from a range of genomic research projects, encompassing targeted, exome and whole genome sequencing from different sequencing platforms and also from different types of clinical material (fresh tissue, formalin fixed paraffin embedded, plasma DNA etc). You will apply analysis methods and where appropriate, develop novel methods and algorithms, and work on setting up and maintaining the necessary data processing pipelines.
You will have a PhD in bioinformatics, statistical genetics or similar discipline with previous postdoctoral experience in applied DNA sequence analysis or directly comparable field. Previous demonstrable experience of analysing next-generation sequencing data is also essential, together with demonstrable programming skills in languages such as Python, Java, C/C++, R or similar. Experience of DNA sequence analysis specifically in cancer is not essential but would be advantageous.
This is a full-time post, available for 3 years in the first instance.
All applicants must complete an application form and submit a CV and supporting statement.
The closing date for applications is 12.00 noon on 20 July 2018.