University of Oxford
UK date and time: 29-May-2017 23:50
 
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Research Assistant in Gene Therapy
Nuffield Division of Clinical Laboratory Sciences, RDM, John Radcliffe Hospital, Oxford
Grade 6: Salary in the range 27,629 - 30,175 p.a.

We are seeking an enthusiastic Research Assistant in Gene Therapy to work with the Gene Medicine Research Group, directed by Associate Professors Deborah Gill and Stephen Hyde.

As part of the UK Cystic Fibrosis Gene Therapy Consortium (UKCFGTC; www.cfgenetherapy.org.uk), we have developed a new lentiviral vector, which efficiently targets the airways. We have been awarded a Cystic Fibrosis Trust grant to aid preparation for a first-in-human clinical trial to investigate the feasibility of this viral gene therapy approach.

The successful applicant will assist in the transfer our current lentiviral production process to a Contract Manufacturing Organisation for the production of cGMP lentiviral vector for the clinical trial. This will include the development of new assays and the evaluation of efficacy of the manufactured vector. The position will also involve the pre-clinical assessment of gene expression and toxicology in support of the clinical trial application. This is a unique opportunity for a research scientist to contribute to the clinical evaluation of a new gene therapy product. The successful candidate will hold a Bachelor's or Master's degree in a relevant science subject, as well as have expertise in molecular biology techniques and relevant laboratory experience in line with the duties of the post, as outlined in the Job Description.

This is a full-time fixed-term position funded by The Cystic Fibrosis Trust until 31 March 2019, available from 1 August 2018.

Candidates are encouraged to discuss their needs and preferences for work arrangements at interview. Applications for this vacancy are to be made online. For further details, including a job description and person specification, please see below.

The closing date for applications is 12.00 noon on 21 June 2017.

Contact Person : Helen Oldham Vacancy ID : 128965
Contact Phone : 01865 220551 Closing Date : 21-Jun-2017
Contact Email : hr@ndcls.ox.ac.uk
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128965_JD_RAGeneTherapy 376
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